Why Make This Recipe
This Melt-in-Your-Mouth Chicken Breast recipe is a fantastic way to serve juicy and creamy chicken with minimal effort. It’s perfect for busy weeknights or even special occasions. The use of mayonnaise or Greek yogurt with Parmesan cheese makes the chicken incredibly tender and flavorful while keeping it super easy to prepare. You’ll love how quickly it cooks and how delicious it turns out!
How to Make Melt-in-Your-Mouth Chicken Breast
Ingredients:
- 4 boneless, skinless chicken breasts
- 1/2 cup mayonnaise or plain Greek yogurt
- 1/2 cup grated Parmesan cheese
- 1 tsp garlic powder
- 1/2 tsp onion powder
- 1/2 tsp paprika
- Salt and black pepper, to taste
- Optional garnish: chopped parsley or chives
Directions:
- Preheat your oven to 375°F (190°C). Lightly grease a 9×13-inch baking dish.
- In a small bowl, mix together the mayonnaise (or yogurt), Parmesan cheese, garlic powder, onion powder, paprika, salt, and pepper.
- Place the chicken breasts in the baking dish and pat them dry with a paper towel.
- Spread the creamy mixture evenly over the top of each chicken breast.
- Bake uncovered for 25–30 minutes, or until the internal temperature reaches 165°F and the topping is golden and bubbly.
- Let the chicken rest for 5 minutes before serving. Garnish with herbs if desired.
How to Serve Melt-in-Your-Mouth Chicken Breast
Serve this creamy and juicy chicken as the main dish for dinner. It pairs well with sides like steamed vegetables, rice, or mashed potatoes. You can also serve it on a bed of greens for a light salad option, or slice it up and use it in sandwiches or wraps for lunch the next day.
How to Store Melt-in-Your-Mouth Chicken Breast
You can store any leftover chicken in an airtight container in the refrigerator for up to 3 days. To reheat, simply place it in the oven at a low temperature until warmed through, or microwave it on a low setting with a splash of water to keep it moist.
Tips to Make Melt-in-Your-Mouth Chicken Breast
- Make sure to pat the chicken dry before applying the creamy mixture; this helps it adhere better and cook evenly.
- For a bit of a kick, add some cayenne pepper or hot sauce into the creamy mixture.
- If you want a crispier topping, broil the chicken for the last 2-3 minutes of baking.
Variation
You can switch out the herbs and spices based on your preference. Try adding Italian seasoning for an herby flavor or experiment with different types of cheese, like mozzarella or cheddar.
FAQs
1. Can I use frozen chicken breasts?
Yes, but it’s best to thaw them completely before preparing this recipe for even cooking.
2. Can I use low-fat mayonnaise or yogurt?
Absolutely. Low-fat options still work well and will create a creamy topping.
3. What if I don’t have Parmesan cheese?
You can substitute it with other hard cheeses like Pecorino Romano or even a blend of shredded cheese for a different flavor profile.

Melt-in-Your-Mouth Chicken Breast
- Prep Time: 15 minutes
- Cook Time: 30 minutes
- Total Time: 45 minutes
- Yield: 4 servings 1x
- Category: Main Course
- Method: Baking
- Cuisine: American
- Diet: Contains Dairy
Description
A juicy and creamy chicken recipe that is easy to prepare and irresistibly delicious, perfect for busy weeknights or special occasions.
Ingredients
- 4 boneless, skinless chicken breasts
- 1/2 cup mayonnaise or plain Greek yogurt
- 1/2 cup grated Parmesan cheese
- 1 tsp garlic powder
- 1/2 tsp onion powder
- 1/2 tsp paprika
- Salt and black pepper, to taste
- Optional garnish: chopped parsley or chives
Instructions
- Preheat your oven to 375°F (190°C). Lightly grease a 9×13-inch baking dish.
- In a small bowl, mix together the mayonnaise (or yogurt), Parmesan cheese, garlic powder, onion powder, paprika, salt, and pepper.
- Place the chicken breasts in the baking dish and pat them dry with a paper towel.
- Spread the creamy mixture evenly over the top of each chicken breast.
- Bake uncovered for 25–30 minutes, or until the internal temperature reaches 165°F and the topping is golden and bubbly.
- Let the chicken rest for 5 minutes before serving. Garnish with herbs if desired.
Notes
Pat the chicken dry before applying the mixture for better adherence. For a crispier topping, broil for the last 2-3 minutes.
Nutrition
- Serving Size: 1 serving
- Calories: 350
- Sugar: 1g
- Sodium: 450mg
- Fat: 25g
- Saturated Fat: 5g
- Unsaturated Fat: 15g
- Trans Fat: 0g
- Carbohydrates: 5g
- Fiber: 0g
- Protein: 30g
- Cholesterol: 100mg







